DEF Injector 1644900513 for Mercedes-Benz Sprinter 2500 3500 E350 S63 AMG ML250 ML350 E350 ML320 GL320 2010-2018
This DEF injector is engineered as a direct replacement for the Mercedes-Benz Sprinter 2500 3500 E350 S63 AMG ML250 ML350 E350 ML320 GL320 2010-2018. Manufactured to meet or exceed OEM specifications, it delivers reliable performance in demanding conditions. Each unit is tested for fuel flow, pressure rating, and durability before leaving the factory to ensure consistent quality across every order.
Vehicle Compatibility
| Application | Details |
|---|---|
| Mercedes | Benz Vehicle: 2012-2013 |
| Mercedes | Benz E 350 4Matic, Base, Bluetec 3.0L V6 – Diesel, 3.5L V6 – Flex, 3.5L V6 – Gas2011 |
| Mercedes | Benz E 350 4Matic, Base, Bluetec 3.0L V6 – Diesel, 3.5L V6 – Gas2009 |
| Mercedes | Benz GL 320 Bluetec 4Matic 3.0L V6 – Diesel2010-2016 |
| Mercedes | Benz GL 350 Bluetec 4Matic 3.0L V6 – Diesel2016 |
| Mercedes | Benz GLE 300d 4Matic 2.1L L4 – Diesel2013-2015 |
| Mercedes | Benz GLK 250 Bluetec 4Matic 2.1L L4 – Diesel2015 |
| Mercedes | Benz ML 250 Bluetec 4Matic 2.1L L4 – Diesel2009 |
| Mercedes | Benz ML 320 Bluetec 4Matic 3.0L V6 – Diesel2010-2014 |
| Mercedes | Benz ML 350 Bluetec 4Matic 3.0L V6 – Diesel2009 |
| Mercedes | Benz R 320 Bluetec 3.0L V6 – Diesel2010-2012 |
| Mercedes | Benz R 350 Bluetec 4Matic 3.0L V6 – Diesel2012-2013 |
Replaces OEM Part Numbers
164-490-05-13 • 164-490-04-13 • 164-490-02-13 • A1644900513 • A1644900213 • A1644900413 • MA1644900513 • 1644900513 • 1644900413 • 1644900213 • Application • Mercedes-Benz
Signs You Need a Replacement
If your equipment is showing any of these symptoms, the injectors & nozzle may be the cause:
- SCR efficiency below threshold (P2047/P2050) — The system detects that the DEF isn’t being dosed correctly. The injector spray pattern is likely degraded or the nozzle is partially blocked.
- White crystallization on injector tip — Contaminated DEF leaves mineral deposits. If you see white buildup, the injector has been exposed to poor-quality or expired fluid.
- Derate or limp mode — The ECU limits engine power to prevent emissions violations when the SCR system can’t keep up. This is the most noticeable symptom.
- DEF consumption suddenly drops — If the tank level doesn’t go down at the normal rate, the injector isn’t spraying. The DEF pump and lines should be checked before replacing the injector.
- Ammonia smell from exhaust — Incomplete DEF mixing in the exhaust stream means the injector isn’t atomizing properly. The SCR reaction needs fine, even distribution.
Installation Notes
Drain the DEF tank before removing the old injector. Flush the DEF line with distilled water to remove any crystallized deposits. When installing the new injector, use the included sealing gasket and torque to specification — over-tightening cracks the injector housing. After installation, fill the tank with fresh DEF only (check the expiration date on the jug). Run the engine for 15 minutes at operating temperature to allow the SCR system to complete its initialization cycle.
Frequently Asked Questions
Will this fit my Mercedes 2500?
Yes. This part is designed to fit the Mercedes 2500, 3500, E350, S63 among other models listed in the compatibility table above. Verify your specific model and engine code before ordering to ensure the correct fit.
Can I cross-reference 164-490-05-13 with 164-490-04-13?
Yes. Both 164-490-05-13 and 164-490-04-13 are interchangeable OEM numbers for this part. They refer to the same component with the same specifications, just different part number revisions.
How do I check if my engine code (ML250, ML350, ML320, GL320) matches?
The engine code is stamped on a metal tag attached to the engine block, usually near the timing belt cover or on the cylinder head. Compare the code you find with the list above. Engine codes are 3 to 6 characters long.
My vehicle is a 2010 model – is it covered?
The compatibility range for this part includes 2010-2018. The 2010 model year falls within this range, but verify the engine code and body type match. Mid-year production changes sometimes mean two vehicles from the same model year use different parts.




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